Abstract     Description     Claims     Drawing  

Molecular cloning: a laboratory manual   [0082] 
Splinkerette PCR for mapping transposable elements in Drosophila   [0141]  [0142] 
A high-throughput Splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites   [0141] 
PCR-based procedures to isolate insertion sites of DNA elements   [0141]  [0142] 
Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain   [0142] 
Breaking the code of DNA binding specificity of TAL-type III effectors   [0142] 
A simple cipher governs DNA recognition by TAL effectors   [0142] 
A TALE nuclease architecture for efficient genome editing   [0142] 
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity   [0142] 
RNA-guided human genome engineering via Cas9   [0142] 
Multiplex Genome Engineering Using CRISPR/Cas Systems   [0142] 
DNA double-strand break repair and development   [0142] 
Playing the end game: DNA double-strand break repair pathway choice   [0142] 
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes   [0142] 
Multicolor CRISPR labeling of chromosomal loci in human cells   [0142] 
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system   [0142] 
Efficient genomic correction methods in human iPS cells using CRISPR-Cas9 system   [0142] 
Advances in therapeutic CRISPR/Cas9 genome editing   [0142] 
Isolation of single-base genome-edited human iPS cells without antibiotic selection   [0142] 
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells   [0142] 
High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells   [0142] 
Small Molecules Enhance CRISPR Genome Editing in Pluripotent Stem Cells   [0142] 
Enriching CRISPR-Cas9 targeted cells by co-targeting the HPRT gene   [0142] 
Surrogate reporters for enrichment of cells with nuclease-induced mutations   [0142] 
Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations   [0142] 
Genetic screens in human cells using the CRISPR-Cas9 system   [0142] 
Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B   [0142] 
ULtiMATE System for Rapid Assembly of Customized TAL Effectors   [0142] 
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases   [0142] 
Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly   [0142] 
A generic strategy for CRISPR-Cas9-mediated gene tagging   [0142] 
CRISPR/Cas9 and TALEN-mediated knock-in approaches in zebrafish   [0142] 
Optimization of Genome Engineering Approaches with the CRISPR/Cas9 System   [0142] 
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology   [0142] 
MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems   [0142] 
Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9   [0142] 
In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration   [0142] 
High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases   [0142] 
A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites   [0142] 
High-throughput screens in mammalian cells using the CRISPR-Cas9 system   [0142]