Description  Claims  Drawing  Cited references 

WO1999065894A   [0003] 
WO2005118565A   [0003] 
US5436238A   [0004]  [0094] 
US5338865A   [0004] 
WO2016003975A   [0004] 
US5786492A   [0005] 
US8598373B   [0005] 
US9206194B   [0005] 
US9469651B   [0005] 
WO2009124237A1   [0005] 
WO1993017690A1   [0005] 
WO2012147900A1   [0005] 
US7982060B   [0005] 
US8618313B   [0005] 
US9303050B   [0005] 
US8093410B   [0005] 
US8350067B   [0005] 
US8975422B   [0005] 
US8987479B   [0005] 
US8203010B   [0005] 
US8445701B   [0005] 
US8884031B   [0005] 
USRE45324E   [0005] 
US8927597B   [0005] 
US9382262B   [0005] 
US9303039B   [0005] 
WO2009046308A1   [0005] 
WO2006076100A3   [0005] 
WO2006076100A2   [0005] 
WO2015085193A1   [0005] 
WO2016176560A1   [0005] 
US9278979B   [0005] 
US9029573B   [0005] 
WO2011094339A1   [0005] 
WO2016179607A1   [0005] 
WO2009064029A1   [0005] 
WO2013142999A1   [0005] 
WO2015066729A1   [0005] 
WO2016038624A1   [0005] 
WO2015000070A1   [0005] 
WO2007139149A   [0040] 
WO9317690A1   [0094] 

Norhalichondrin A: An Antitumor Polyether Macrolide from a Marine Sponge   [0002]  [0136]  [0136]  [0136]  [0136] 
Total Synthesis of Halichondrin B and Norhalichondrin B   [0002] 
Halichondrins-antitumor polyether macrolides from a marine sponge   [0002] 
Comparative antitumor activities of halichondrins and vinblastine against human tumor xenografts   [0002] 
Macrocyclic ketone analogues of halichondrin B   [0003] 
Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome   [0006] 
Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in esophageal adenocarcinoma   [0006] 
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer   [0006] 
Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer   [0006] 
The tumor stromal features are associated with resistance to 5-FU-based chemoradiotherapy and a poor prognosis in patients with oral squamous cell carcinoma   [0006] 
Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models   [0007] 
Synthetic Studies Towards Halichondrins: Synthesis of the Left Halves of Norhalichondrins and Homohalichondrins   [0007] 
Antitumour polyether macrolides: Four new halichondrins from the New Zealand deep-water marine sponge Lissodendoryx sp   [0007] 
J. Pharmaceutical Sciences   [0022] 
J. Mass Spectrum. Soc. Jpn.   [0040] 
Japanese Pharmacopoeia   [0046] 
European Pharmacopoeia   [0046] 
Organic Letters   [0074] 
CHEMICAL ABSTRACTS   [0074] 
CHEMICAL ABSTRACTS   [0094] 
Organic Letters   [0123] 
CHEMICAL ABSTRACTS   [0123] 
Journal of the American Chemical Society   [0123] 
CHEMICAL ABSTRACTS   [0123] 
Journal of the American Chemical Society   [0123] 
CHEMICAL ABSTRACTS   [0123] 
CHEMICAL ABSTRACTS   [0123] 
Antitumor Polyether Macrolides: New and Hemisynthetic Halichondrins from the New Zealand Deep-Water Sponge Lissodendoryx sp.   [0136]