Abstract     Description     Claims     Drawing  

WO2010072703A   [0004] 

Abundance of cytochromes P450 in human liver: a meta-analysis   [0128]  [0142] 
The conduct of in vitro and in vivo drug-drug interaction studies: A Pharmaceutical Research and Manufacturers of America (PhRMA) perspective   [0142] 
In vitro techniques for studying drug metabolism   [0142] 
Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes   [0142] 
In vitro approaches for studying the inhibition of drug-metabolizing enzymes and identifying the drug-metabolizing enzymes responsible for the metabolism of drugs (Reaction phenotyping) with emphasis on cytochrome P450   [0142] 
Clinical and toxicological relevance of CYP2C9: drug-drug interactions and pharmacogenetics   [0142] 
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians   [0142] 
Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential-towards a consensus   [0142] 
S1 Enzyme kinetics Module Version 1.1 for SigmaPlot   [0143] 
S2 Simcyp Version 4.10.02   [0143]