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2010-12-09T16:45:25+01:00
2010-11-02T06:45:26Z
2010-12-09T16:45:25+01:00
Jouve S.A., EPO - Publication - KB, TaggedPDF v1.27
EP-0329481-A2-19890823
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EP-0329481-A2-19890823
Anchimeric chelating compounds which are capable of rapidly forming stable chelates with radionuclide metals at or below physiological temperatures are disclosed. The compounds possess a first site capable of complexing with a radionuclide metal which can be transferred to a second site (to form a chelate) by incubation, such as at 37°C or below. These anchimeric chelating compounds may be bifunctional and so are useful for radiolabelling target specific molecules such as monoclonal antibodies and fragments thereof, that may be specific for cancer cells.
Anchimeric chelating compounds which are capable of rapidly forming stable chelates with radionuclide metals at or below physiological temperatures are disclosed. The compounds possess a first site capable of complexing with a radionuclide metal which can be transferred to a second site (to form a chelate) by incubation, such as at 37°C or below. These anchimeric chelating compounds may be bifunctional and so are useful for radiolabelling target specific molecules such as monoclonal antibodies and fragments thereof, that may be specific for cancer cells.
en
European Patent Office
EP0329481
EP 0329481
A61K 43/00
A61K 49/02
C07C161/04
C07K 05/02
C07K 05/06
G01N 33/534
Anchimeric radiometal chelating compounds
Anchimeric radiometal chelating compounds - European Patent Office - EP 0329481 A2
Anchimeric radiometal chelating compounds - European Patent Office - EP 0329481 A2
Adobe PDF Library 8.0
"EP0329481"; "EP 0329481"; "A61K 43/00"; "A61K 49/02"; "C07C161/04"; "C07K 05/02"; "C07K 05/06"; "G01N 33/534"; "Anchimeric radiometal chelating compounds"
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1989-02-17
US
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1988-02-17
A61K 43/00
A61K 49/02
C07C161/04
C07K 05/02
C07K 05/06
G01N 33/534
NEORX CORPORATION
Fritzberg, Alan R.
Srinivasan, Ananthachari
Sheard, Andrew Gregory et al
Anchimeric radiometal chelating compounds
Anchimere Radiometallchelat bildende Verbindungen
Anchimeric radiometal chelating compounds
Composés anchimères et radiométal chélatants
Anchimeric chelating compounds which are capable of rapidly forming stable chelates with radionuclide metals at or below physiological temperatures are disclosed. The compounds possess a first site capable of complexing with a radionuclide metal which can be transferred to a second site (to form a chelate) by incubation, such as at 37°C or below. These anchimeric chelating compounds may be bifunctional and so are useful for radiolabelling target specific molecules such as monoclonal antibodies and fragments thereof, that may be specific for cancer cells.
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