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EP-0204523-A3-19881123
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EP-0204523-A3-19881123
Polyiodothyronine analog conjugates to glucose-6-phosphate dehydrogenase (G6PDH) are provided which find use in the determination of polyiodothyronine compounds, particularly thyroxine, normally in physiological fluids, such as serum. The G6PDH enzyme activity can be substantially reduced when bound to antibodies specific to polyiodothyronine as compared to the free or unbound polyiodothyronine analog enzyme conjugates. The polyiodothyronine analog is conjugated to the G6PDH by a linking group having a chain one atom in length.
Polyiodothyronine analog conjugates to glucose-6-phosphate dehydrogenase (G6PDH) are provided which find use in the determination of polyiodothyronine compounds, particularly thyroxine, normally in physiological fluids, such as serum. The G6PDH enzyme activity can be substantially reduced when bound to antibodies specific to polyiodothyronine as compared to the free or unbound polyiodothyronine analog enzyme conjugates. The polyiodothyronine analog is conjugated to the G6PDH by a linking group having a chain one atom in length.
en
European Patent Office
EP0204523
EP 0204523
C12N 09/96
G01N 33/78
C12Q 01/54
Glucose-6-phosphate dehydrogenase conjugates, their preparation and use
Glucose-6-phosphate dehydrogenase conjugates, their preparation and use - European Patent Office - EP 0204523 A3
Glucose-6-phosphate dehydrogenase conjugates, their preparation and use - European Patent Office - EP 0204523 A3
Adobe PDF Library 8.0
"EP0204523"; "EP 0204523"; "C12N 09/96"; "G01N 33/78"; "C12Q 01/54"; "Glucose-6-phosphate dehydrogenase conjugates, their preparation and use"
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0204523
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1988-11-23
86304125
1986-05-30
US
739732
1985-05-31
C12N 09/96
G01N 33/78
C12Q 01/54
SYNTEX (U.S.A.) INC.
Khanna, Pyare
Schulkamp, Kirk
Armitage, Ian Michael et al
Glucose-6-phosphate dehydrogenase conjugates, their preparation and use
Konjugate von Glucose-6-phosphat-dehydrogenase, ihre Herstellung und Verwendung
Glucose-6-phosphate dehydrogenase conjugates, their preparation and use
Conjugés de la déhydrogénase de glucose-6-phosphate, leur préparation et leur utilisation
Polyiodothyronine analog conjugates to glucose-6-phosphate dehydrogenase (G6PDH) are provided which find use in the determination of polyiodothyronine compounds, particularly thyroxine, normally in physiological fluids, such as serum. The G6PDH enzyme activity can be substantially reduced when bound to antibodies specific to polyiodothyronine as compared to the free or unbound polyiodothyronine analog enzyme conjugates. The polyiodothyronine analog is conjugated to the G6PDH by a linking group having a chain one atom in length.
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