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EP-0320154-A1-19890614
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EP-0320154-A1-19890614
A urine screen comprises carrying out at least two separate assays on portions of a sample. One assay detects the presence of leucocytes and the other detects the presence of bacterial cells. Each assay has as the product of reaction with the species to be detected a compound and both compounds can be detected optically at the same predetermined wavelength, usually by automated apparatus. A preferred test for leucocytes uses a synthetic substrate for leucocyte elastase. A preferred test for bacteria uses a synthetic substrate for the endotoxin sensitive limulus amoebocyte lysate. Preferably the products of the hydrolytic cleavage of both substrates include the same fluorescent compound.
A urine screen comprises carrying out at least two separate assays on portions of a sample. One assay detects the presence of leucocytes and the other detects the presence of bacterial cells. Each assay has as the product of reaction with the species to be detected a compound and both compounds can be detected optically at the same predetermined wavelength, usually by automated apparatus. A preferred test for leucocytes uses a synthetic substrate for leucocyte elastase. A preferred test for bacteria uses a synthetic substrate for the endotoxin sensitive limulus amoebocyte lysate. Preferably the products of the hydrolytic cleavage of both substrates include the same fluorescent compound.
en
European Patent Office
EP0320154
EP 0320154
C12Q 01/38
G01N 33/579
Body fluid assay and kit
Body fluid assay and kit - European Patent Office - EP 0320154 A1
Body fluid assay and kit - European Patent Office - EP 0320154 A1
Adobe PDF Library 8.0
"EP0320154"; "EP 0320154"; "C12Q 01/38"; "G01N 33/579"; "Body fluid assay and kit"
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0320154
A1
1989-06-14
88311208
1988-11-25
GB
8727796
1987-11-27
C12Q 01/38
G01N 33/579
RADIOMETER CORPORATE DEVELOPMENT LIMITED
Grist, Roger William
Jones, Helen Marjorie Meredith et al
Body fluid assay and kit
Test- und Reagenzsatz für Körperflüssigkeit
Body fluid assay and kit
Essai et trousse de réactifs pour liquide corporel
A urine screen comprises carrying out at least two separate assays on portions of a sample. One assay detects the presence of leucocytes and the other detects the presence of bacterial cells. Each assay has as the product of reaction with the species to be detected a compound and both compounds can be detected optically at the same predetermined wavelength, usually by automated apparatus. A preferred test for leucocytes uses a synthetic substrate for leucocyte elastase. A preferred test for bacteria uses a synthetic substrate for the endotoxin sensitive limulus amoebocyte lysate. Preferably the products of the hydrolytic cleavage of both substrates include the same fluorescent compound.
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