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2010-10-30T18:56:23+01:00
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Jouve S.A., EPO - Publication - KB, TaggedPDF v1.27
EP-0295961-A3-19890712
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EP-0295961-A3-19890712
A polysaccharide produced from a procaryotic or eucaryotic organism and useful as an antiviral agent, especially an antiretroviral agenct, has the following properties:(a) (i) positive results when subjected to the α-naphthol-sulfuric acid, indole-sulfuric acid, anthrone-sulfuric acid or phenol-sulfuric acid reaction, or(ii) positive results when subjected to the α-naphthol-sulfuric acid, indole-sulfuric acid, anthrone-sulfuric acid or phenol-sulfuric acid reaction and, after hydrochloric acid hydrolysis, to the Lowry-Folin process or ninhydrin reaction;(b) elementary analysis: 20-55% carbon, 3-9% hydrogen and less than 16% nitrogen;(c) a pH of 6.0-7.5;(d) an infrared absorption spectrum peak at(i) 3600-3200 cm⁻¹ or(ii) 3600-3200 cm⁻¹ and 1700-1600 cm⁻¹;(e) a molecular weight of from 10³ to 3 x 10⁶ as measured by gel filtration chromatography; and(f) soluble in water and aqueous solvents containing water-soluble alcohols, acids or bases and insoluble in chloroform, benzene and ether.
A polysaccharide produced from a procaryotic or eucaryotic organism and useful as an antiviral agent, especially an antiretroviral agenct, has the following properties:(a) (i) positive results when subjected to the α-naphthol-sulfuric acid, indole-sulfuric acid, anthrone-sulfuric acid or phenol-sulfuric acid reaction, or(ii) positive results when subjected to the α-naphthol-sulfuric acid, indole-sulfuric acid, anthrone-sulfuric acid or phenol-sulfuric acid reaction and, after hydrochloric acid hydrolysis, to the Lowry-Folin process or ninhydrin reaction;(b) elementary analysis: 20-55% carbon, 3-9% hydrogen and less than 16% nitrogen;(c) a pH of 6.0-7.5;(d) an infrared absorption spectrum peak at(i) 3600-3200 cm⁻¹ or(ii) 3600-3200 cm⁻¹ and 1700-1600 cm⁻¹;(e) a molecular weight of from 10³ to 3 x 10⁶ as measured by gel filtration chromatography; and(f) soluble in water and aqueous solvents containing water-soluble alcohols, acids or bases and insoluble in chloroform, benzene and ether.
en
European Patent Office
EP0295961
EP 0295961
C12P 21/00
A61K 35/66
A61K 35/70
A61K 35/72
A61K 35/74
A61K 35/84
Polysaccharides and antiviral drug containing polysaccharides as active ingredient
Polysaccharides and antiviral drug containing polysaccharides as active ingredient - European Patent Office - EP 0295961 A3
Polysaccharides and antiviral drug containing polysaccharides as active ingredient - European Patent Office - EP 0295961 A3
Adobe PDF Library 8.0
"EP0295961"; "EP 0295961"; "C12P 21/00"; "A61K 35/66"; "A61K 35/70"; "A61K 35/72"; "A61K 35/74"; "A61K 35/84"; "Polysaccharides and antiviral drug containing polysaccharides as active ingredient"
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0295961
A3
1989-07-12
88305582
1988-06-17
JP
15208587
1987-06-18
JP
15208987
1987-06-18
JP
15209087
1987-06-18
JP
15209187
1987-06-18
C12P 21/00
A61K 35/66
A61K 35/70
A61K 35/72
A61K 35/74
A61K 35/84
KUREHA KAGAKU KOGYO KABUSHIKI KAISHA
Hirose, Kunitaka
Furusho, Takao
Muto, Shigeaki
Niimura, Koichi
Oohara, Minoru
Oguchi, Yoshiharu
Matsunaga, Kenichi
Kakuchi, Junji
Sugita, Norifumi
Yoshikumi, Chikao
Takahashi, Masaaki
Woods, Geoffrey Corlett
Polysaccharides and antiviral drug containing polysaccharides as active ingredient
Polysaccharide und antivirale Medikamente mit Polysacchariden als wirksamer Inhaltsstoff
Polysaccharides and antiviral drug containing polysaccharides as active ingredient
Polysaccharides et médicaments anti-viraux les contenant comme principe actif
A polysaccharide produced from a procaryotic or eucaryotic organism and useful as an antiviral agent, especially an antiretroviral agenct, has the following properties:(a) (i) positive results when subjected to the α-naphthol-sulfuric acid, indole-sulfuric acid, anthrone-sulfuric acid or phenol-sulfuric acid reaction, or(ii) positive results when subjected to the α-naphthol-sulfuric acid, indole-sulfuric acid, anthrone-sulfuric acid or phenol-sulfuric acid reaction and, after hydrochloric acid hydrolysis, to the Lowry-Folin process or ninhydrin reaction;(b) elementary analysis: 20-55% carbon, 3-9% hydrogen and less than 16% nitrogen;(c) a pH of 6.0-7.5;(d) an infrared absorption spectrum peak at(i) 3600-3200 cm⁻¹ or(ii) 3600-3200 cm⁻¹ and 1700-1600 cm⁻¹;(e) a molecular weight of from 10³ to 3 x 10⁶ as measured by gel filtration chromatography; and(f) soluble in water and aqueous solvents containing water-soluble alcohols, acids or bases and insoluble in chloroform, benzene and ether.
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