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EP-0265050-A1-19880427
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EP-0265050-A1-19880427
Mitomycin derivatives having potent antitumour activity having the formula:wherein X is -->(wherein Ra, Rb and Rc each independently represent lower alkyl, cycloalkyl having 3-7 carbon atoms or phenyl; or Ra and Rb are bonded together to form a poly-methylene group having 2-5 carbon atoms); one of R1 and R2 represents carbamoyloxymethyl and the other represents hydrogen; or R1 and R2 may together form an exocyclic methylene group; and Y and Z each independently represents hydrogen or methyl.
Mitomycin derivatives having potent antitumour activity having the formula:wherein X is -->(wherein Ra, Rb and Rc each independently represent lower alkyl, cycloalkyl having 3-7 carbon atoms or phenyl; or Ra and Rb are bonded together to form a poly-methylene group having 2-5 carbon atoms); one of R1 and R2 represents carbamoyloxymethyl and the other represents hydrogen; or R1 and R2 may together form an exocyclic methylene group; and Y and Z each independently represents hydrogen or methyl.
en
European Patent Office
EP0265050
EP 0265050
C07D 487/14
C07F 09/65
A61K 31/40
C07D487/14
C07D209/00
C07D209/00
C07D203/00
Mitomycin derivatives
Mitomycin derivatives - European Patent Office - EP 0265050 A1
Mitomycin derivatives - European Patent Office - EP 0265050 A1
Adobe PDF Library 8.0
"EP0265050"; "EP 0265050"; "C07D 487/14"; "C07F 09/65"; "A61K 31/40"; "C07D487/14"; "C07D209/00"; "C07D209/00"; "C07D203/00"; "Mitomycin derivatives"
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1986-08-26
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A61K 31/40
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C07D209/00
C07D209/00
C07D203/00
KYOWA HAKKO KOGYO KABUSHIKI KAISHA
Kono, Motomichi
Morimoto, Makoto
Kasai, Masaji
Ashizawa, Tadashi
Saito, Yutaka
Hildyard, Edward Martin et al
Mitomycin derivatives
Mitomycin-Derivate
Mitomycin derivatives
Dérivés de mitomycine
Mitomycin derivatives having potent antitumour activity having the formula:wherein X is -->(wherein Ra, Rb and Rc each independently represent lower alkyl, cycloalkyl having 3-7 carbon atoms or phenyl; or Ra and Rb are bonded together to form a poly-methylene group having 2-5 carbon atoms); one of R1 and R2 represents carbamoyloxymethyl and the other represents hydrogen; or R1 and R2 may together form an exocyclic methylene group; and Y and Z each independently represents hydrogen or methyl.
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