(19)
(11) EP 0 005 006 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
14.11.1979 Bulletin 1979/23

(43) Date of publication A2:
31.10.1979 Bulletin 1979/22

(21) Application number: 79300371

(22) Date of filing: 12.03.1979
(84) Designated Contracting States:
BE CH DE FR GB IT NL SE

(30) Priority: 21.04.1978 GB 1580778

(71) Applicant: BEECHAM GROUP PLC
 ()

(72) Inventors:
  • Rogers, Norman Harold
     ()
  • O'Hanlon, Peter John
     ()

   


(54) Antibacterial compounds, processes for their preparation and compositions containing them


(57) Monic acid C and its salts and esters of formula (II):

where R is a salt-forming ion or pharmaceutically acceptably ester-forming radical may be prepared by either converting the epoxide in the known monic acid A to an olefin, or by hydrolysis of the naturally occurring pseudomonic acid C. The esters of monic acid C have antibacterial and anti-mycoplasma activity and are therefore useful in the treatment of human and veterinary bacterial and mycoplasma- induced infections.





Search report