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(11)

EP 2 834 367 A1

(12)

(43) Date of publication: 11.02.2015 Bulletin 2015/07 (21) Application number: 13773119.6 (22) Date of filing: 04.04.2013

(51) International Patent Classification (IPC):  C12Q 1/02(2006.01) G01N 33/48(2006.01) C12Q 1/68(2006.01) C12M 1/34(2006.01) (86) International application number: PCT/US2013/035291 (87) International publication number: WO 2013/152203 (10.10.2013 Gazette 2013/41)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME (30) Priority: 05.04.2012 US 201261620823 P (71) Applicant: Becton Dickinson and Company Franklin Lakes, NJ 07417 (US)

(72) Inventors: LI, Xiao Germantown, MD 20874 (US) ZHANG, Yongqiang Lutherville, MD 21093 (US) KOPHER, Kenneth, Anthony Baltimore, MD 21221 (US) MANTLO, John, D. Westminster, MD 21158 (US) POPE, William, Alfred Owings Mills, MD 21117 (US) SHI, Song Reisterstown, MD 21136 (US) YUP, Axel, A. Owings Mills, MD 21117 (US) (74) Representative: Vossius & Partner  Siebertstrasse 4 81675 München 81675 München (DE)