(57) Isoxazolo-(5,4-C)-pyridine derivatives of the formula
in which R" is hydrogen, acetyl or a group of the formula R5OCO- in which Rs is C1-4-alkyl, phenyl, substituted phenyl; phenylalkyl or substituted phenylalkyl and salts
thereof, and intermediates IV, VIII', IX' and V.
Compounds (I) may be prepared according to the following reaction scheme:
in which Z is hydrogen or a protecting group, T is a group convertible by hydrolysis
into an oxo group, Q is a leaving group and W is hydrogen or a group removable to
yield the free hydroxy group.
Compounds (I) exhibit a y-aminobutyric acid related activity and are useful as active
ingredients in pharmaceutical compositions which may, optionally, further contain
a minor tranquilizer or a neuroleptic.
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