(19)

(11)

EP 0 030 560 A1

(12)

(43) Date of publication: 24.06.1981 Bulletin 1981/25 (21) Application number: 80901384.0 (22) Date of filing: 20.06.1980

(51) International Patent Classification (IPC):  C07K 16/ 40( . ) C12Q 1/ 28( . ) A61K 38/ 00( . ) C12N 9/ 08( . ) G01N 33/ 74( . ) (86) International application number: PCT/US1980/000813 (87) International publication number: WO 1980/002800 (24.12.1980 Gazette 1980/29)

(84) Designated Contracting States: AT CH DE FR GB LI LU NL SE (30) Priority: 21.06.1979 US 19790050810 (71) Applicants: OSTER, Gerald New York, NY 10014 (US) KESTON, Albert S. Weehawken, NJ 07087 (US)	(72) Inventors: OSTER, Gerald New York, NY 10014 (US) KESTON, Albert S. Weehawken, NJ 07087 (US) (74) Representative: Ellis, Edward Lovell  MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)