(19)

(11)

EP 0 056 401 A1

(12)

(43) Date of publication: 28.07.1982 Bulletin 1982/30 (21) Application number: 81902146.0 (22) Date of filing: 15.07.1981

(51) International Patent Classification (IPC):  A61K 31/ 195( . ) A61K 31/ 405( . ) (86) International application number: PCT/US1981/000963 (87) International publication number: WO 1982/000250 (04.02.1982 Gazette 1982/04)

(84) Designated Contracting States: AT CH DE FR GB LI NL SE (30) Priority: 15.07.1980 US 19800169001 (71) Applicant: WURTMAN, Richard J. Boston, MA 02116 (US)	(72) Inventor: WURTMAN, Richard J. Boston, MA 02116 (US)