(19)

(11)

EP 0 096 074 A1

(12)

(43) Date of publication: 21.12.1983 Bulletin 1983/51 (21) Application number: 83900393.0 (22) Date of filing: 20.12.1982

(51) International Patent Classification (IPC):  A61K 31/ 04( . ) A61K 9/ 22( . ) A61K 31/ 13( . ) A61K 9/ 00( . ) A61K 9/ 28( . ) A61K 31/ 49( . ) (86) International application number: PCT/US1982/001771 (87) International publication number: WO 1983/002056 (23.06.1983 Gazette 1983/15)

(84) Designated Contracting States: AT BE CH DE FR GB LI LU NL SE (30) Priority: 18.12.1981 US 19810332126 18.12.1981 US 19810332127 18.12.1981 US 19810332128 (71) Applicant: Key Pharmaceuticals, Inc. Miami, Florida 33169 (US)	(72) Inventor: KEITH, Alec Miami, FL 33169 (US) (74) Representative: Werner, Hans-Karsten, Dr., et al  Patentanwälte Von Kreisler-Selting-Werner Postfach 10 22 41 D-50462 Köln D-50462 Köln (DE)