(19)

(11)

EP 0 118 489 A1

(12)

(43) Date of publication: 19.09.1984 Bulletin 1984/38 (21) Application number: 83902757.0 (22) Date of filing: 22.08.1983

(51) International Patent Classification (IPC):  C07C 45/ 59( . ) (86) International application number: PCT/GB1983/000207 (87) International publication number: WO 1984/000956 (15.03.1984 Gazette 1984/07)

(84) Designated Contracting States: CH DE FR GB LI NL (30) Priority: 27.08.1982 GB 19820024653 (71) Applicant: BEECHAM GROUP PLC Brentford Middlesex TW8 9BD (GB)	(72) Inventors: HINDLEY, Richard, Mark Surrey (GB) CANTELLO, Barrie, Christian, Charles Surrey (GB)