(19)

(11)

EP 0 125 269 A1

(12)

(43) Date of publication: 21.11.1984 Bulletin 1984/47 (21) Application number: 83903560.0 (22) Date of filing: 10.11.1983

(51) International Patent Classification (IPC):  C12N 9/ 72( . ) A61K 38/ 00( . ) (86) International application number: PCT/GB1983/000284 (87) International publication number: WO 1984/001960 (24.05.1984 Gazette 1984/13)

(84) Designated Contracting States: CH DE FR GB LI NL (30) Priority: 11.11.1982 GB 19820032228 (71) Applicant: BEECHAM GROUP PLC Brentford Middlesex TW8 9BD (GB)	(72) Inventors: SMITH, Richard, Anthony, Godwin Surrey (GB) ROBINSON, Jeffery, Hugh Surrey (GB)