(19)
(11) EP 0 147 689 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
04.11.1987 Bulletin 1987/45

(43) Date of publication A2:
10.07.1985 Bulletin 1985/28

(21) Application number: 84114813

(22) Date of filing: 05.12.1984
(84) Designated Contracting States:
DE FR GB IT

(30) Priority: 05.12.1983 JP 22849683
29.05.1984 JP 10760584
02.10.1984 JP 20555984
05.10.1984 JP 20806684
15.10.1984 JP 21432684
15.10.1984 JP 21432784

(71) Applicant: Asahi Kasei Kogyo Kabushiki Kaisha
 ()

(72) Inventors:
  • Kaieda, Takeji
     ()
  • Yamada, Kimimasa
     ()
  • Yamawaki, Naokuni
     ()

   


(54) A method of inducing antitumor immunocytes, and a process for producing antitumor immunocytes and antitumor immunocytes produced by the process


(57) A method of inducing antitumor immunocytes which is simple in operation and suitable for inducing antitumor immunocytes having not only excellent cytotoxic activity against tumor cells but also high safety, which method comprises contacting leucocytes with an insoluble, antitumor immunocyte-inducing material capable of linking with T cells, said antitumor immunocyte-inducing material comprising an insoluble carrier and a ligand linked therewith. The induced antitumor immunocytes can be simply separated in substantially ligand-free form from the insoluble, antitumor immunocyte-inducing material. The obtained antitumor immunocytes have not only excellent cytotoxic activity against tumor cells but also high safety.






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