(19)

(11)

EP 0 160 089 A1

(12)

(43) Date of publication: 06.11.1985 Bulletin 1985/45 (21) Application number: 84904239.0 (22) Date of filing: 25.10.1984

(51) International Patent Classification (IPC):  A01C 1/ 08( . ) C07K 14/ 24( . ) A01N 63/ 00( . ) (86) International application number: PCT/US1984/001741 (87) International publication number: WO 1985/001878 (09.05.1985 Gazette 1985/11)

(84) Designated Contracting States: AT BE CH DE FR GB LI LU NL SE (30) Priority: 26.10.1983 US 19830545722 (71) Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Berkeley, California 94720 (US)	(72) Inventors: VAN GUNDY, Seymour, D. Riverside, CA 92507 (US) ZAVALETA-MEJIA, Emma Riverside, CA 92507 (US) (74) Representative: Harrison, David Christopher, et al  MEWBURN ELLIS York House 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)