(19)

(11)

EP 0 168 401 A1

(12)

(43) Date of publication: 22.01.1986 Bulletin 1986/04 (21) Application number: 84901593.0 (22) Date of filing: 23.03.1984

(51) International Patent Classification (IPC):  A23K 1/ 16( . ) A61K 39/ 00( . ) A61K 39/ 39( . ) C07K 16/ 18( . ) A61D 7/ 00( . ) A61K 39/ 385( . ) C07K 7/ 23( . ) C07K 16/ 26( . ) (86) International application number: PCT/GB1984/000092 (87) International publication number: WO 1984/003629 (27.09.1984 Gazette 1984/23)

(84) Designated Contracting States: BE DE FR GB NL SE (30) Priority: 25.03.1983 GB 19830008330 (71) Applicant: NATIONAL RESEARCH DEVELOPMENT CORPORATION London SE1 6BU (GB)	(72) Inventor: NATIONAL RESEARCH DEVELOPMENT CORPORATION London SE1 6BU (GB) (74) Representative: Colmer, Stephen Gary  Patent Department National Research Development Corporation 101 Newington Causeway London SE1 6BU London SE1 6BU (GB)