(19)

(11)

EP 0 169 239 A1

(12)

(43) Date of publication: 29.01.1986 Bulletin 1986/05 (21) Application number: 85901141.0 (22) Date of filing: 11.01.1985

(51) International Patent Classification (IPC):  C12N 15/ 00( . ) C07K 14/ 195( . ) C07K 14/ 52( . ) C07K 19/ 00( . ) C12N 15/ 09( . ) A61K 38/ 00( . ) C07K 14/ 005( . ) C07K 14/ 505( . ) C07K 16/ 22( . ) C12N 1/ 20( . ) C12P 21/ 00( . ) C12R 1/ 19( . ) (86) International application number: PCT/US1985/000054 (87) International publication number: WO 1985/003079 (18.07.1985 Gazette 1985/16)

(84) Designated Contracting States: AT BE CH DE FR GB LI LU NL SE (30) Priority: 11.01.1984 US 19840570040 (71) Applicant: NEW YORK UNIVERSITY New York, NY 10012 (US)	(72) Inventor: LEE-HUANG, Sylvia New York, NY 10021 (US) (74) Representative: Patentanwälte Grünecker, Kinkeldey, Stockmair & Partner  Maximilianstrasse 58 D-80538 München D-80538 München (DE)