(19)
(11) EP 0 178 321 A1

(12)

(43) Date of publication:
23.04.1986 Bulletin 1986/17

(21) Application number: 85902306.0

(22) Date of filing: 17.04.1985
(51) International Patent Classification (IPC): 
A61K 9/ 70( . )
A61K 38/ 28( . )
(86) International application number:
PCT/US1985/000695
(87) International publication number:
WO 1985/005036 (21.11.1985 Gazette 1985/25)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 30.04.1984 US 19840605608

(71) Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
New York, New York 10027 (US)

(72) Inventors:
  • WEBER, Collin, J.
    Leonia, NJ 07605 (US)
  • KAZIM, Michael
    Riverdale, NY 10463 (US)
  • REEMTSMA, Keith
    New York, NY 10024 (US)
  • NICHOLSON, John, F.
    New York, NY 10032 (US)

   


(54) TOPICAL TREATMENT OF DIABETES WITH INSULIN AND PENETRANT ENHANCER APPLIED TO THE SKIN AND COVERED BY A PATCH