(19)
(11) EP 0 183 822 A1

(12)

(43) Date of publication:
11.06.1986 Bulletin 1986/24

(21) Application number: 85903113.0

(22) Date of filing: 31.05.1985
(51) International Patent Classification (IPC): 
G01N 33/ 50( . )
G01N 33/ 58( . )
C12Q 1/ 68( . )
(86) International application number:
PCT/US1985/001026
(87) International publication number:
WO 1985/005685 (19.12.1985 Gazette 1985/27)
(84) Designated Contracting States:
CH DE FR GB IT LI NL SE

(30) Priority: 01.06.1984 US 19840616205

(71) Applicant: National Biomedical Research Foundation
Washington D.C. 20007 (US)

(72) Inventors:
  • ZAPOLSKI, Edward, J.
    Arlington, VA 22207 (US)
  • GERSTEN, Douglas, M.
    Washington, DC 20007 (US)
  • LEDLEY, Robert, S.
    Silver Spring, MD 20903 (US)

(74) Representative: Bannerman, David Gardner 
Withers & Rogers 4 Dyer's Buildings Holborn
London, EC1N 2JT
London, EC1N 2JT (GB)

   


(54) CATALYZED NUCLEIC ACID HYBRIDIZATION USING ENZYMATIC REAGENT