(57) The present invention provides a composition for cleaning drains clogged with a hair-containing deposit which comprises: (a) a hair-disintegrating amount of a proteolytic enzyme, (b) a disulfide reducing agent, and (c) an alkali metal bisulfite compound in an amount sufficient to enhance the rate of activity of the enzyme, wherein the components (a), (b) and (c) are present as dispersions, separately or in combination, in water-soluble beads, each comprising a water-soluble polymer, such that the enzyme and reducing agent cannot substantially cross-react prior to dissolution of the beads, and wherein the composition on dissolution provides a pH that enhances hair denaturation.