(19)

(11)

EP 0 186 692 A1

(12)

(43) Date of publication: 09.07.1986 Bulletin 1986/28 (21) Application number: 85903101.0 (22) Date of filing: 29.05.1985

(51) International Patent Classification (IPC):  C12N 9/ 96( . ) G01N 33/ 561( . ) G01N 33/ 58( . ) G01N 33/ 535( . ) G01N 33/ 577( . ) G01N 33/ 68( . ) (86) International application number: PCT/US1985/000992 (87) International publication number: WO 1985/005638 (19.12.1985 Gazette 1985/27)

(84) Designated Contracting States: DE FR GB IT SE (30) Priority: 29.05.1984 IL 19470000719 (71) Applicants: WILCHEK, Meir Rehovot (IL) BAYER, Edward A. Raanana (IL) GERSHONI, Jonathan M. Rehovot (IL)	(72) Inventors: WILCHEK, Meir Rehovot (IL) BAYER, Edward A. Raanana (IL) GERSHONI, Jonathan M. Rehovot (IL) (74) Representative: Ritter, Stephen David, et al  Mathys & Squire 100 Grays Inn Road London WC1X 8AL London WC1X 8AL (GB)