(19) |
 |
|
(11) |
EP 0 187 130 A3 |
(12) |
EUROPEAN PATENT APPLICATION |
(88) |
Date of publication A3: |
|
02.09.1987 Bulletin 1987/36 |
(43) |
Date of publication A2: |
|
09.07.1986 Bulletin 1986/28 |
(22) |
Date of filing: 23.12.1985 |
|
|
(84) |
Designated Contracting States: |
|
AT BE CH DE FR GB IT LI LU NL SE |
(30) |
Priority: |
28.12.1984 US 687323
|
(71) |
Applicant: Monsanto Company |
|
() |
|
(72) |
Inventors: |
|
- Pulwer, Mitchell Joel
()
- Balthazor, Terry Mack
()
- Rogers, Thomas Edward
()
|
|
|
|
(54) |
Process for producing N-substituted alpha-amino acids |
(57) Secondary or tertiary alpha-amino acids are providedin high yield in one step by
the reductive amination of glyoxylic acid in a reaction medium comprising glyoxylic
acid, a primary or secondary amine, and water in an atmosphere of hydrogen using a
palladium hydrogenation catalyst.