(19)

(11)

EP 0 197 111 A1

(12)

(43) Date of publication: 15.10.1986 Bulletin 1986/42 (21) Application number: 85905072.0 (22) Date of filing: 11.10.1985

(51) International Patent Classification (IPC):  A61K 35/ 12( . ) A61K 38/ 00( . ) A61M 1/ 36( . ) A61K 35/ 14( . ) A61M 1/ 00( . ) (86) International application number: PCT/GB1985/000457 (87) International publication number: WO 1986/002274 (24.04.1986 Gazette 1986/09)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 12.10.1984 GB 19840025783 (71) Applicants: SERALAB LIMITED Sussex RH10 4FF (GB) COUNCIL OF GOVERNORS OF THE UNITED MEDICAL AND DENTAL SCHOOLS OF GUY'S AND ST. THOMAS'S HOSPITALS London, S.W. 1 (GB)	(72) Inventor: LEHNER, Thomas 'Chesters' Barnet, Hertfordshire, EN4 OLL (GB) (74) Representative: Hedley, Nicholas James Matthew, et al  Stephenson Harwood One, St. Paul's Churchyard London EC4M 8SH London EC4M 8SH (GB)