(19)

(11)

EP 0 197 985 A1

(12)

(43) Date of publication: 22.10.1986 Bulletin 1986/43 (21) Application number: 85904943.0 (22) Date of filing: 26.09.1985

(51) International Patent Classification (IPC):  A01N 25/ 00( . ) A01N 47/ 44( . ) A61K 8/ 84( . ) A61Q 17/ 00( . ) C11D 3/ 37( . ) G02C 7/ 04( . ) A01N 25/ 30( . ) A61K 8/ 43( . ) A61L 12/ 14( . ) C11D 3/ 00( . ) C11D 3/ 48( . ) G02C 13/ 00( . ) (86) International application number: PCT/US1985/001880 (87) International publication number: WO 1986/002001 (10.04.1986 Gazette 1986/08)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 28.09.1984 US 19840655965 11.12.1984 US 19840680450 (71) Applicant: BAUSCH & LOMB INCORPORATED Rochester New York 14609 (US)	(72) Inventors: OGUNBIYI, Lai Fairport, NY 14450 (US) SMITH, Francis, X. Walworth, NY 14563 (US) RIEDHAMMER, Thomas, M. Toms River, NJ 08753 (US) (74) Representative: Allam, Peter Clerk, et al  LLOYD WISE, TREGEAR & CO. Norman House 105-109 Strand London WC2R 0AE London WC2R 0AE (GB)