(19)

(11)

EP 0 211 029 A1

(12)

(43) Date of publication: 25.02.1987 Bulletin 1987/09 (21) Application number: 86900813.0 (22) Date of filing: 23.01.1986

(51) International Patent Classification (IPC):  A61K 39/ 145( . ) C12N 7/ 04( . ) (86) International application number: PCT/GB1986/000044 (87) International publication number: WO 1986/004242 (31.07.1986 Gazette 1986/17)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 28.01.1985 GB 19850002096 (71) Applicant: MEDICAL RESEARCH COUNCIL London W1N 4AL (GB)	(72) Inventors: ASKONAS, Brigitte, Alice The Ridgeway Mill Hill London NW7 1AA (GB) WRAITH, David, Cameron The Ridgeway Mill Hill London NW7 1AA (GB) (74) Representative: Goldin, Douglas Michael, et al  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)