(19)
(11)
EP 0 215 058 A1
(12)
(43)
Date of publication:
25.03.1987
Bulletin 1987/13
(21)
Application number:
86901647.0
(22)
Date of filing:
21.02.1986
(51)
International Patent Classification (IPC):
C07D
487/
00
( . )
C07D
471/
20
( . )
C07D
487/
10
( . )
C07D
519/
04
( . )
A61K
31/
475
( . )
C07D
487/
04
( . )
C07D
519/
00
( . )
(86)
International application number:
PCT/US1986/000334
(87)
International publication number:
WO 1986/005491
(
25.09.1986
Gazette 1986/21)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
12.03.1985
US 19850710792
(71)
Applicant:
THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE
Burlington, VT 05405 (US)
(72)
Inventor:
KUEHNE, Martin
Burlington, VT 05401 (US)
(74)
Representative:
Grossner, Lutz, Dr., et al
Grenzacher Strasse 124 Postfach 3255
CH-4002 Basel
CH-4002 Basel (CH)
(54)
SYNTHESIS OF VINBLASTINE AND VINCRISTINE TYPE COMPOUNDS