(19)

(11)

EP 0 230 407 A1

(12)

(43) Date of publication: 05.08.1987 Bulletin 1987/32 (21) Application number: 85903888.0 (22) Date of filing: 19.07.1985

(51) International Patent Classification (IPC):  A61B 5/ 113( . ) A61B 7/ 00( . ) (86) International application number: PCT/SE1985/000288 (87) International publication number: WO 1987/000415 (29.01.1987 Gazette 1987/03)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (71) Applicant: KAROLINSKA INSTITUTET S-104 01 Stockholm 60 (SE)	(72) Inventors: LINNARSSON, Dag S-182 75 Stocksund (SE) TEDNER, Bo S-139 00 Värmdö (SE)