(19)

(11)

EP 0 231 356 A1

(12)

(43) Date of publication: 12.08.1987 Bulletin 1987/33 (21) Application number: 86905052.0 (22) Date of filing: 31.07.1986

(51) International Patent Classification (IPC):  A61K 33/ 00( . ) A61K 31/ 765( . ) A61P 1/ 10( . ) A61K 9/ 08( . ) A61K 33/ 14( . ) A61P 3/ 00( . ) (86) International application number: PCT/US1986/001578 (87) International publication number: WO 1987/000754 (12.02.1987 Gazette 1987/04)

(84) Designated Contracting States: CH DE FR GB IT LI (30) Priority: 01.08.1985 US 19850761577 (71) Applicant: BRAINTREE LABORATORIES, INC. Braintree, MA 02184 (US)	(72) Inventor: FORDTRAN, John, S. Dallas, TX 75225 (US) (74) Representative: Slight, Geoffrey Charles, et al  Graham Watt & Co. Riverhead Sevenoaks Kent TN13 2BN Sevenoaks Kent TN13 2BN (GB)