(19)

(11)

EP 0 239 629 A1

(12)

(43) Date of publication: 07.10.1987 Bulletin 1987/41 (21) Application number: 86906533.0 (22) Date of filing: 29.09.1986

(51) International Patent Classification (IPC):  C12Q 1/ 68( . ) (86) International application number: PCT/US1986/002048 (87) International publication number: WO 1987/002059 (09.04.1987 Gazette 1987/08)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 30.09.1985 US 19850782663 30.05.1986 US 19860869177 26.08.1986 US 19860900593 (71) Applicant: BIOTECHNOLOGY RESEARCH PARTNERS, LTD. Mountain View California 94043 (US)	(72) Inventor: FROSSARD, Philippe, M. Palo Alto, CA 94306 (US) (74) Representative: Goldin, Douglas Michael, et al  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)