(57) Compounds of the formula
 [wherein
R1 represents a methyl group;
R2 represents a methyl group
R3 represents a methyl, ethyl or isopropyl group; and
-A- represents a ring which is either

(where R4 is a hydroxy or methoxy group and R5 is a hydrogen atom or R4 and R5 together with the carbon atom to which they are attached represent a group C=0);
or when -A-represents ring (ii) wherein R4 and R5 together with the carbon atom to which they are attached represent a group C=0 then
R2 may also represent an aldehydo group;
or R2 represents a hydroxymethyl group and -A- represents
 (where R6 represents a hydrogen atom or a hydroxy group);

(where R7 is a hydroxy or methoxy group and Z represents either a group CHOH or a group C=0);
or R1 represents a hydrogen atom and

(where R8 is a hydroxy or methoxy group); with the provisos that when R2 represents a methyl group and R4 represents a methoxy group then R3 cannot represents a methyl or isopropyl group and when R2 represents a hydroxymethyl group and R6 represents a hydroxy group then R3 cannot represent a methyl group. Compounds of the invention have antiparasitic activity.
|