(19)

(11)

EP 0 244 427 A1

(12)

(43) Date of publication: 11.11.1987 Bulletin 1987/46 (21) Application number: 86905164.0 (22) Date of filing: 29.08.1986

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C07K 14/ 00( . ) C07K 14/ 445( . ) C07K 16/ 00( . ) C12N 15/ 62( . ) C12P 21/ 08( . ) A61K 39/ 285( . ) C07K 14/ 44( . ) C07K 14/ 705( . ) C12N 7/ 00( . ) C12N 15/ 863( . ) A61K 39/ 00( . ) (86) International application number: PCT/AU1986/000256 (87) International publication number: WO 1987/001386 (12.03.1987 Gazette 1987/06)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 29.08.1985 AU 19850002198 (71) Applicant: THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH Parkville, VIC 3050 (AU)	(72) Inventors: LANGFORD, Christopher, John Brunswick West, VIC 3055 (AU) EDWARDS, Stirling, John Eltham, VIC 3095 (AU) (74) Representative: Holmes, Michael John, et al  Frank B. Dehn & Co. European Patent Attorneys Imperial House 15-19 Kingsway London, WC2B 6UZ, London, WC2B 6UZ, (GB)