(19)
(11) EP 0 245 432 A1

(12)

(43) Date of publication:
19.11.1987 Bulletin 1987/47

(21) Application number: 86907042.0

(22) Date of filing: 21.10.1986
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
A61K 38/ 00( . )
C07K 14/ 00( . )
C07K 14/ 195( . )
C07K 16/ 00( . )
C12N 15/ 02( . )
C12P 21/ 08( . )
C12R 1/ 91( . )
A61K 35/ 18( . )
C07K 1/ 20( . )
C07K 14/ 005( . )
C07K 14/ 52( . )
C07K 16/ 24( . )
C12P 21/ 00( . )
G01N 33/ 577( . )
(86) International application number:
PCT/US1986/002226
(87) International publication number:
WO 1987/002677 (07.05.1987 Gazette 1987/10)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL SE

(30) Priority: 22.10.1985 US 19850789997

(71) Applicants:
  • JEWISH HOSPITAL OF ST. LOUIS
    St. Louis, MO 63110 (US)
  • F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft
    CH-4002 Basel (CH)

(72) Inventors:
  • PIERCE, Carl, W.
    St. Louis, MO 63131 (US)
  • WEBB, David, R., Jr.
    West Orange, NJ 07052 (US)

(74) Representative: Lederer, Franz, Dr., et al 
Lederer, Keller & Riederer Patentanwälte Prinzregentenstrasse 16
D-80538 München
D-80538 München (DE)

(74) Representative: Mezger, Wolfgang, Dr., et al 
Grenzacherstrasse 124 Postfach 3255
CH-4002 Basel
CH-4002 Basel (CH)

   


(54) ISOFORMS OF SOLUBLE IMMUNE RESPONSE SUPPRESSOR