(19)
(11) EP 0 249 618 A1

(12)

(43) Date of publication:
23.12.1987 Bulletin 1987/52

(21) Application number: 87900104.0

(22) Date of filing: 05.12.1986
(51) International Patent Classification (IPC): 
A61K 31/ 16( . )
A61K 35/ 74( . )
A61K 38/ 19( . )
A61K 31/ 65( . )
A61K 38/ 00( . )
A61K 45/ 06( . )
(86) International application number:
PCT/EP1986/000710
(87) International publication number:
WO 1987/003489 (18.06.1987 Gazette 1987/13)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 05.12.1985 US 19850805853

(71) Applicant: BIOGEN N.V.
Willemstad CuraƧao Netherlands Antilles (NL)

(72) Inventors:
  • FIERS, Walter, Charles
    B-9120 Destelbergen (BE)
  • FRANSEN, Lucia, Marie
    B-9000 Gent (BE)
  • VAN DER HEYDEN, Jose
    B-9242 Munte (BE)

(74) Representative: Bannerman, David Gardner, et al 
Withers & Rogers 4 Dyer's Buildings Holborn
London, EC1N 2JT
London, EC1N 2JT (GB)

   


(54) COMBINATIONS OF TUMOR NECROSIS FACTORS AND ANTIBIOTICS AND METHODS FOR TREATING TUMORS