(19)

(11)

EP 0 250 523 A1

(12)

(43) Date of publication: 07.01.1988 Bulletin 1988/01 (21) Application number: 87900213.0 (22) Date of filing: 17.12.1986

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12N 15/ 70( . ) C12N 1/ 20( . ) C12P 21/ 02( . ) (86) International application number: PCT/GB1986/000773 (87) International publication number: WO 1987/003909 (02.07.1987 Gazette 1987/14)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 17.12.1985 GB 19850031069 (71) Applicant: CELLTECH LIMITED Slough Berkshire SL1 4DY (GB)	(72) Inventor: BROWN, Michael, Edward Berkshire SL1 5ST (GB) (74) Representative: Votier, Sidney David, et al  CARPMAELS & RANSFORD 43, Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)