(19)

(11)

EP 0 250 557 A1

(12)

(43) Date of publication: 07.01.1988 Bulletin 1988/01 (21) Application number: 87900526.0 (22) Date of filing: 12.12.1986

(51) International Patent Classification (IPC):  C12Q 1/ 26( . ) G01N 33/ 543( . ) G01N 33/ 53( . ) G01N 33/ 58( . ) (86) International application number: PCT/US1986/002681 (87) International publication number: WO 1987/003691 (18.06.1987 Gazette 1987/13)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 12.12.1985 US 19850807936 (71) Applicant: Dennison Manufacturing Company Framingham, MA 01701 (US)	(72) Inventor: COLE, Francis Stow, MA 01775 (US) (74) Representative: Robinson, Anthony John Metcalf, et al  Kilburn & Strode 30 John Street London, WC1N 2DD London, WC1N 2DD (GB)