(19)
(11) EP 0 252 144 A1

(12)

(43) Date of publication:
13.01.1988 Bulletin 1988/02

(21) Application number: 87900925.0

(22) Date of filing: 06.01.1987
(51) International Patent Classification (IPC): 
C07C 43/ 196( . )
C07C 35/ 18( . )
C07C 41/ 00( . )
C07C 49/ 753( . )
C07C 69/ 013( . )
C07D 303/ 00( . )
C07C 27/ 00( . )
C07C 35/ 48( . )
C07C 49/ 713( . )
C07C 67/ 00( . )
C07C 69/ 145( . )
C07D 303/ 32( . )
(86) International application number:
PCT/US1987/000020
(87) International publication number:
WO 1987/004159 (16.07.1987 Gazette 1987/15)
(84) Designated Contracting States:
DE FR GB IT

(30) Priority: 08.01.1986 US 19860817136

(71) Applicant: HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC.
Fort Pierce, FL 33450 (US)

(72) Inventors:
  • HIGA, Tatsuo
    Naha, Ohinawa (JP)
  • SCHEUER, Paul, J.
    Honolulu, Hawaii 96822 (US)

(74) Representative: Marchant, James Ian 
Elkington and Fife Prospect House 8 Pembroke Road
Sevenoaks, Kent TN13 1XR
Sevenoaks, Kent TN13 1XR (GB)

   


(54) ANTITUMOR CYCLOHEXANONE COMPOSITIONS AND DERIVATIVES THEREOF