(19)

(11)

EP 0 256 117 A1

(12)

(43) Date of publication: 24.02.1988 Bulletin 1988/08 (21) Application number: 87901829.0 (22) Date of filing: 04.02.1987

(51) International Patent Classification (IPC):  G01N 33/ 532( . ) G01N 33/ 58( . ) G01N 33/ 543( . ) (86) International application number: PCT/US1987/000245 (87) International publication number: WO 1987/004794 (13.08.1987 Gazette 1987/18)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 06.02.1986 US 19860827325 (71) Applicant: MICROBIOLOGICAL ASSOCIATES, INC. Bethesda, MD 20816 (US)	(72) Inventors: FUCCILLO, David, A. Rockville, MD 29854 (US) SHEKARCHI, Isabel, C. Bethesda, MD 20817 (US)