(19)

(11)

EP 0 258 241 A1

(12)

(43) Date of publication: 09.03.1988 Bulletin 1988/10 (21) Application number: 86902853.0 (22) Date of filing: 22.04.1986

(51) International Patent Classification (IPC):  A61K 8/ 00( . ) A61K 8/ 21( . ) A61K 33/ 42( . ) A61K 6/ 033( . ) A61K 8/ 24( . ) A61Q 11/ 00( . ) (86) International application number: PCT/GB1986/000222 (87) International publication number: WO 1986/006274 (06.11.1986 Gazette 1986/24)

(84) Designated Contracting States: CH DE GB LI (30) Priority: 23.04.1985 GB 19850010310 (71) Applicant: NATIONAL RESEARCH DEVELOPMENT CORPORATION London SE1 6BU (GB)	(72) Inventor: CAUSTON, Brian, Edward 38 St. John's Rise Surrey GU21 1PW (GB) (74) Representative: Marshall, Monica Anne, et al  GALLAFENT & CO. 8 Staple Inn London WC1V 7QH London WC1V 7QH (GB)