(19)

(11)

EP 0 262 118 A1

(12)

(43) Date of publication: 06.04.1988 Bulletin 1988/14 (21) Application number: 86900945.0 (22) Date of filing: 16.01.1986

(51) International Patent Classification (IPC):  C12N 9/ 04( . ) C12P 19/ 02( . ) C12P 7/ 58( . ) (86) International application number: PCT/US1986/000082 (87) International publication number: WO 1987/004460 (30.07.1987 Gazette 1987/17)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI NL SE (71) Applicant: CETUS CORPORATION Emeryville California 94608 (US)	(72) Inventors: KOTHS, Kirston, E. El Cerrito, CA 94530 (US) HALENBECK, Robert, F. San Rafael, CA 94901 (US) FERNANDES, Peter, M. Walnut Creek, CA 94596 (US) RING, David, B. Redwood City, CA 94061 (US)