(19)

(11)

EP 0 265 478 A1

(12)

(43) Date of publication: 04.05.1988 Bulletin 1988/18 (21) Application number: 87902630.0 (22) Date of filing: 27.04.1987

(51) International Patent Classification (IPC):  C07K 16/ 12( . ) A61K 38/ 00( . ) (86) International application number: PCT/GB1987/000278 (87) International publication number: WO 1987/006468 (05.11.1987 Gazette 1987/24)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 25.04.1986 GB 19860010204 (71) Applicant: TECHNOLOGY LICENCE COMPANY LIMITED Douglas, Isle of Man (GB)	(72) Inventors: WRIGHT, Bruce, William Cambridgeshire CB3 7EG (GB) COX, Peter, John Church Cottage Bury St. Edmunds Suffolk IP19 5QH (GB) NOYES, Alice, Margaret Cambridgeshire CB4 5ES (GB) WIDDOWS, Danny Cambridge CB4 1RT (GB) DOWSON, Anne Cambridgeshire CB6 2NH (GB) CLARK, Julie Huntingdon PE17 2AN (GB) REID, John, Homan Cambridge CB3 7DB (GB)