(19)
(11) EP 0 282 011 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
25.10.1989 Bulletin 1989/43

(43) Date of publication A2:
14.09.1988 Bulletin 1988/37

(21) Application number: 88103642.0

(22) Date of filing: 08.03.1988
(51) International Patent Classification (IPC)4: A61K 9/28, A61K 9/22
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 09.03.1987 US 23424

(71) Applicant: WARNER-LAMBERT COMPANY
Morris Plains New Jersey 07950 (US)

(72) Inventors:
  • Khan, Sadath U.
    Mine Hill New Jersey 07801 (US)
  • Chakraborty, Pijush K.
    Maplewood New Jersey 07040 (US)
  • Grabowski, Albert T.
    Dover New Jersey 07801 (US)
  • Phillips, Reginald
    Coral Spring Florida 33065 (US)

(74) Representative: Mansmann, Ivo 
Gödecke AG Patentwesen Mooswaldallee 1-9
79090 Freiburg
79090 Freiburg (DE)


(56) References cited: : 
   
       


    (54) Sustained release pharmaceutical dosage forms


    (57) A unique sustained release dosage form which prevents the tendency of an initial surge of medicament in the first hour of administration. The control is by a porous membrance coating. The amount of initial release can be varied by varying the proportions of the components of the coatings.





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