(19)
(11) EP 0 288 477 A1

(12)

(43) Date of publication:
02.11.1988 Bulletin 1988/44

(21) Application number: 87900539.0

(22) Date of filing: 15.12.1986
(51) International Patent Classification (IPC): 
C07C( . )
A61K 31/ 135( . )
A61K 31/ 40( . )
A61K 31/ 535( . )
C07C 209/ 00( . )
C07C 215/ 64( . )
C07C 225/ 20( . )
C07C 229/ 50( . )
C07C 317/ 36( . )
C07C 323/ 52( . )
C07D 317/ 10( . )
C07C 323/ 38( . )
A61K 31/ 395( . )
A61K 31/ 445( . )
C07C 67/ 00( . )
C07C 213/ 00( . )
C07C 219/ 26( . )
C07C 227/ 00( . )
C07C 313/ 00( . )
C07C 323/ 12( . )
C07D 205/ 04( . )
C07D 319/ 06( . )
(86) International application number:
PCT/US1986/002698
(87) International publication number:
WO 1987/004153 (16.07.1987 Gazette 1987/15)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 31.12.1985 US 19850815367

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventors:
  • SZMUSZKOVICZ, Jacob
    Kalamazoo, MI 49008 (US)
  • DARLINGTON, William, H.
    Kalamazoo, MI 49009 (US)
  • VON VOIGTLANDER, Philip, F.
    Plainwell, MI 49080 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS