(19)
(11)
EP 0 288 477 A1
(12)
(43)
Date of publication:
02.11.1988
Bulletin 1988/44
(21)
Application number:
87900539.0
(22)
Date of filing:
15.12.1986
(51)
International Patent Classification (IPC):
C07C
( . )
A61K
31/
135
( . )
A61K
31/
40
( . )
A61K
31/
535
( . )
C07C
209/
00
( . )
C07C
215/
64
( . )
C07C
225/
20
( . )
C07C
229/
50
( . )
C07C
317/
36
( . )
C07C
323/
52
( . )
C07D
317/
10
( . )
C07C
323/
38
( . )
A61K
31/
395
( . )
A61K
31/
445
( . )
C07C
67/
00
( . )
C07C
213/
00
( . )
C07C
219/
26
( . )
C07C
227/
00
( . )
C07C
313/
00
( . )
C07C
323/
12
( . )
C07D
205/
04
( . )
C07D
319/
06
( . )
(86)
International application number:
PCT/US1986/002698
(87)
International publication number:
WO 1987/004153
(
16.07.1987
Gazette 1987/15)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
31.12.1985
US 19850815367
(71)
Applicant:
THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)
(72)
Inventors:
SZMUSZKOVICZ, Jacob
Kalamazoo, MI 49008 (US)
DARLINGTON, William, H.
Kalamazoo, MI 49009 (US)
VON VOIGTLANDER, Philip, F.
Plainwell, MI 49080 (US)
(74)
Representative:
Perry, Robert Edward, et al
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)
(54)
2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS