(19)
(11) EP 0 288 488 A1

(12)

(43) Date of publication:
02.11.1988 Bulletin 1988/44

(21) Application number: 87905838.0

(22) Date of filing: 17.08.1987
(51) International Patent Classification (IPC): 
C07D 233/ 66( . )
C07D 233/ 84( . )
(86) International application number:
PCT/US1987/002011
(87) International publication number:
WO 1988/001267 (25.02.1988 Gazette 1988/05)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 18.08.1986 US 19860898165

(71) Applicant: SMITHKLINE BECKMAN CORPORATION
Philadelphia Pennsylvania 19103 (US)

(72) Inventors:
  • FINKELSTEIN, Joseph, Alan
    Philadelphia, PA 19151 (US)
  • FRAZEE, James, Simpson
    Sewell, NJ 08080 (US)
  • KAISER, Carl
    Haddon Heights, NJ 08080 (US)
  • KRUSE, Lawrence, Ivan
    Tewin Herfordshire AL6 0NY (GB)
  • LEONARD, Thomas, Brent
    Haverford, PA 19041 (US)

(74) Representative: Giddings, Peter John, Dr., et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) DOPAMINE- -HYDROXYLASE INHIBITORS