(19)

(11)

EP 0 289 587 A1

(12)

(43) Date of publication: 09.11.1988 Bulletin 1988/45 (21) Application number: 88900052.0 (22) Date of filing: 18.11.1987

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) A61P 13/ 02( . ) A61K 38/ 22( . ) A61P 15/ 00( . ) (86) International application number: PCT/US1987/003038 (87) International publication number: WO 1988/003928 (02.06.1988 Gazette 1988/12)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 18.11.1986 US 19860932069 (71) Applicant: SENETEK PLC Maryland Heights, MO 63043 (US)	(72) Inventors: FAHRENKRUG, Jan DK-2900 Hellerup (DK) OTTESEN, Bent DK-1920 Frederiksberg C (DK) (74) Representative: Bizley, Richard Edward, et al  BOULT, WADE & TENNANT 27 Furnival Street London EC4A 1PQ London EC4A 1PQ (GB)