(19)

(11)

EP 0 297 107 A1

(12)

(43) Date of publication: 04.01.1989 Bulletin 1989/01 (21) Application number: 87901924.0 (22) Date of filing: 20.02.1987

(51) International Patent Classification (IPC):  C07C 67/ 28( . ) (86) International application number: PCT/US1987/000376 (87) International publication number: WO 1987/005010 (27.08.1987 Gazette 1987/19)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 20.02.1986 US 19860830141 (71) Applicant: PHARMACONTROL CORP. Englewood Cliffs, NJ 07632 (US)	(72) Inventor: DUCATMAN, Fred, P. Westfield, NJ 07090 (US) (74) Representative: Jump, Timothy John Simon, et al  Venner Shipley & Co. 20 Little Britain London EC1A 7DH London EC1A 7DH (GB)