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(11)

EP 0 297 110 A1

(12)

(43) Date of publication: 04.01.1989 Bulletin 1989/01 (21) Application number: 87902028.0 (22) Date of filing: 13.03.1987

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C07K 7/ 06( . ) C07K 14/ 00( . ) C07K 14/ 445( . ) C07K 19/ 00( . ) C12N 1/ 16( . ) C12N 1/ 20( . ) C12Q 1/ 68( . ) A61K 39/ 00( . ) C12R 1/ 645( . ) A61K 39/ 015( . ) C07K 7/ 08( . ) C07K 14/ 44( . ) C07K 16/ 00( . ) C12N 1/ 14( . ) C12N 1/ 19( . ) C12P 21/ 02( . ) G01N 33/ 569( . ) C12R 1/ 19( . ) (86) International application number: PCT/AU1987/000071 (87) International publication number: WO 1987/005607 (24.09.1987 Gazette 1987/21)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 14.03.1986 AU 19860005045 23.04.1986 AU 19860005595 (71) Applicant: SARAMANE PTY. LTD. Parkville, VIC 3052 (AU)

(72) Inventors: ANDERS, Robin, Fredric North Melbourne, VIC 3051 (AU) KEMP, David, James North Balwyn, VIC 3104 (AU) BROWN, Graham, Vallancey Balwyn, VIC 3103 (AU) COPPEL, Ross, Leon Armadale, VIC 3143 (AU) MITCHELL, Graham, Frank Lower Templestowe, VIC 3107 (AU) WOODROW, Graeme, Charles West Lindfield, NSW 2070 (AU) TETAZ, Timothy, John Willoughby, NSW 2068 (AU) GOSS, Neil, Howard Wahroonga, NSW 2076 (AU) (74) Representative: Holmes, Michael John, et al  Frank B. Dehn & Co. European Patent Attorneys Imperial House 15-19 Kingsway London, WC2B 6UZ, London, WC2B 6UZ, (GB)