(19)
(11)
EP 0 301 083 A1
(12)
(43)
Date of publication:
01.02.1989
Bulletin 1989/05
(21)
Application number:
88902298.0
(22)
Date of filing:
09.02.1988
(51)
International Patent Classification (IPC):
C07K
14/
02
( . )
A61K
38/
00
( . )
C12N
15/
85
( . )
A61K
39/
00
( . )
(86)
International application number:
PCT/US1988/000380
(87)
International publication number:
WO 1988/006185
(
25.08.1988
Gazette 1988/19)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
11.02.1987
US 19870013562
08.02.1988
US 19880154117
(71)
Applicant:
SCRIPPS CLINIC AND RESEARCH FOUNDATION
La Jolla California 92037 (US)
(72)
Inventors:
McLACHLAN, Alan
San Diego, CA 92130 (US)
MILICH, David, R.
Mira Mesa, CA 92126 (US)
SORGE, Joseph
Del Mar Highlands, CA 92130 (US)
(74)
Representative:
Fisher, Adrian John, et al
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)
(54)
RETROVIRAL EXPRESSION VECTORS AND METHODS FOR PRODUCING HBV ANTIGENS